Beilstein J. Org. Chem.2022,18, 1070–1078, doi:10.3762/bjoc.18.109
cytotoxic agents.
Keywords: 1,4-dihydroisoquinol-3-one; heterocyclicdiazocompounds; hydroarylation; Regitz diazo transfer; triflic acid; Introduction
Besides being derivatives of (or a precursor to) the 1,2,3,4-tetrahydroisoquinoline core which itself bears a special significance from the standpoint of
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Graphical Abstract
Figure 1:
Diverse bioactive compounds based on the privileged 1,4-DHIQ scaffold.